Author

Hailey R. Olafson

University of Florida

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

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Amrutha Pattamatta· 1 shared Eric T. WangiD· 1 shared J. Andrew BerglundiD· 1 shared Jared I. Richardson· 1 shared Laura P.W. RanumiD· 1 shared Lauren A. LaboissonniereiD· 1 shared Lien NguyeniD· 1 shared Marina M. Scotti· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperNeuroscience

Amrutha Pattamatta

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1 paper

Recent·Most cited

NeuroscienceHuman Molecular GeneticsPeer-reviewedDec 15, 2020

Repeat length increases disease penetrance and severity in C9orf72 ALS/FTD BAC transgenic mice

Amrutha Pattamatta, Lien Nguyen, Hailey R. Olafson…·Laura P.W. Ranum

This study shows longer G4C2 repeats in C9orf72 transgenic mice lead to earlier disease onset, higher penetrance, and more RNA foci, with alternative splicing changes as early biomarkers.

19 citations

mouseexperimental assay

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