Author

Hanbing Cao

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Kaiyuan TangiD· 3 shared Medha MajetyiD· 3 shared Shao‐Yu FangiD· 3 shared Sidi CheniD· 3 shared Xiaoyu ZhouiD· 3 shared Andrew DuiD· 2 shared Erica Vandenbulcke· 2 shared Jerry ZhouiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Kaiyuan TangORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 2, 2026

Engineered CTLA-4 targeting chimeras for targeted protein degradation and immune synapse reprogramming

Ping Ren, Shao‐Yu Fang, 赵姝姝…·Xiaoyu Zhou

This paper introduces cTACs, synthetic molecules that degrade PD-L1 across immune and tumor cells, enhancing T cell activation and tumor suppression in vivo.

DOI 10.64898/2026.09.29.755403

humanprotein structure

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BioengineeringbioRxivPreprintMar 14, 2024

High-fidelity enhanced AsCas12a knock-in mice for efficient multiplexed gene editing, disease modeling and orthogonal immunogenetics

Kaiyuan Tang, Xiaoyu Zhou, Shao‐Yu Fang…·Sidi Chen

DOI 10.1101/2024.03.14.585126

mousegenetic perturbation / CRISPR

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GeneticsbioRxivPreprintMar 14, 2023

Cas12a/Cpf1 knock-in mice enable efficient multiplexed immune cell engineering

Matthew B. Dong, Kaiyuan Tang, Xiaoyu Zhou…·Sidi Chen

The paper demonstrates efficient multiplexed gene editing in immune cells using Cas12a/Cpf1 knock-in mice and associated viral vectors.

5 citations

mouseexperimental assay

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