GenomicsNucleic Acids ResearchPeer-reviewed
To mock or not: a comprehensive comparison of mock IP and DNA input for ChIP-seq
Jinrui Xu, Michelle M. Kudron, Alec Victorsen…·Mark Gerstein
This study compares mock IP and DNA input controls in ChIP-seq, showing that mock IP better removes spurious sites, while DNA input has unique advantages, and proposes combining both for improved binding site detection.