Author

Heather Hansen

West Virginia University

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Bradley A. WebbiD· 1 shared Eric M. LynchiD· 1 shared Justin M. KollmaniD· 1 shared Lauren E. SalayiD· 1 shared Madison P. CooperiD· 1 shared Štěpán TimriD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiochemistry

Bradley A. WebbORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedAug 25, 2024

Structural basis for allosteric regulation of human phosphofructokinase-1

Eric M. Lynch, Heather Hansen, Lauren E. Salay…·Bradley A. Webb

This study determines the cryoEM structures of human PFK1 in R- and T-states, revealing eukaryotic allosteric regulation mechanisms and the role of the C-terminus in autoinhibition.

75 citationstop 1%

humanstructural biology

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