Cell BiologyEMBO ReportsPeer-reviewed
CtBP restricts DUX-dependent and -independent genetic program for the 2-cell-like state in murine embryonic stem cells
Kazuma Yoshioka, Maki Ichisakino, Kota Sugiyama…·Yoshiyuki Seki
The paper shows that Ctbp1/2 disruption activates DUX-dependent and -independent pathways in mESCs, leading to 2-cell-like state features through PRAMEL7 upregulation.
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