Cancer BiologybioRxivPreprint
Control of MYC-dependent apoptotic threshold by a co-amplified ubiquitin E3 ligase UBR5
Xi Qiao, Ying Liu, Maria Llamazares Prada…·Jukka Westermarck
This study identifies UBR5 as a novel MYC ubiquitin ligase that regulates MYC protein stability and apoptotic threshold in cancer cells and breast tissue.
DOI 10.1101/515247