ImmunologybioRxivPreprint
Senescent cells induce vascular MHC II to recruit CD4+ T cells and drive inflammation in aging adipose tissue
Qijing Xie, Tzu‐Hua Lin, SoRi Jang…·Cynthia J. Kenyon
This study identifies senescent cells as drivers of age-related inflammation in adipose tissue by inducing vascular MHC II and recruiting CD4+ T cells through an IFN-gamma feedback loop.
DOI 10.64898/2026.05.13.724992