Developmental BiologyAmerican Journal of Physiology-Renal PhysiologyPeer-reviewed
Tcf21 as a Founder Transcription Factor in Specifying Foxd1 Cells to the Juxtaglomerular Cell Lineage
Hina Anjum, Jason P. Smith, Alexandre G. Martini…·Gal Finer
This study identifies Tcf21 as essential for Foxd1+ progenitor cells to differentiate into juxtaglomerular cells during kidney development, showing reduced renin expression and altered renal morphology when Tcf21 is inactivated.