ImmunologybioRxivPreprint
HIF isoforms contribute distinctly during human NK cell activation
Jorrit De Waele, Tias Verhezen, Ho Wa Lau…·Evelien Smits
This study investigates the distinct roles of HIF-1 and HIF-2 in human NK cell activation under normoxic conditions, finding that HIF-1 inhibition reduces cytotoxicity and cytokine production while HIF-2 has no effect.
DOI 10.1101/2025.06.27.661904