Cancer BiologyNAR CancerPeer-reviewed
HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
Hongbo Ling, Yixuan Li, Changmin Peng…·Edward Seto
This study shows that inhibiting HDAC10 increases SPARC expression, which suppresses melanoma growth and restores sensitivity to BRAF inhibitors.
14 citations