Author

Hubert Schelzig

Düsseldorf University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:differential expression· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Agnes Bosbach· 3 shared Kim Jürgen KrottiD· 3 shared Margitta ElversiD· 3 shared Markus Udo WagenhäuseriD· 3 shared Tobias Feige· 3 shared Irena Krüger· 2 shared Madhumita ChatterjeeiD· 2 shared Norbert GerdesiD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersPathology

Agnes Bosbach

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dysregulated Platelet GPIb alpha - VWF Signalling in Abdominal Aortic Aneurysm formation and Progression

Tobias Feige, Kim Jürgen Krott, Agnes Bosbach, M Chario, J Ortscheid, A Saleem, MU Wagenhäuser, Hubert Schelzig, Margitta Elvers

This study identifies dysregulated GPIb alpha-VWF signalling in AAA, showing increased platelet GPIb alpha expression and VWF activity in patients and mice.

bioRxiv · Sep 25, 2026 · PreprintPathology

Crosstalk between thrombospondin-1 and CD36 modulates platelet-RBC interaction limiting thrombosis and abdominal aneurysm formation

Kim Jürgen Krott, Tobias Feige, Agnes Bosbach, Alicia Beele, Irena Krüger, Friedrich Reusswig, Elena Schickentanz-Dey, Susanne Pfeiler, Alexandra Chadt, Malte Kelm, Norbert Gerdes, Kerstin Jurk, Klytaimnistra Kiouptsi, Christoph Reinhardt, Hadi Al‐Hasani, , Margitta Elvers

This study identifies a novel CD36-TSP-1 signaling pathway that modulates platelet-RBC interaction, promoting thrombus formation and contributing to abdominal aortic aneurysm pathology.

Circulation Research · Oct 27, 2025Peer-reviewedPathology

Olfactory receptor 2 drives abdominal aortic aneurysm by promoting CX3CR1-mediated monocyte recruitment

Patrik Schelemei, Felix S.R. Picard, Yein Park, Philipp Wollnitzke, Harshal Nemade, Dennis Mehrkens, Per Arkenberg, Anna Christine Koebele, Jan Wrobel, Kristel Martinez Lagunas, Elena Wagner, Henning Guthoff, Joy Roy, Moritz Lindquist Liljeqvist, Wiebke Ibing, , Holger Winkels

This study shows that Olfr2 promotes abdominal aortic aneurysm by enhancing CX3CR1-mediated monocyte recruitment through inflammatory pathways.

bioRxiv · Feb 28, 2025 · PreprintImmunology

Crosstalk of platelets with macrophages and fibroblasts aggravates inflammation, aortic wall stiffening, and osteopontin release in abdominal aortic aneurysm

Markus Udo Wagenhäuser, Joscha U Mulorz, Kim Jürgen Krott, Agnes Bosbach, Tobias Feige, Yae Hyun Rhee, Madhumita Chatterjee, Niklas Petzold, Christopher Böddeker, Wiebke Ibing, Irena Krüger, Ana M Popovic, Ann N. Roseman, Joshua Michael Spin, Philip S. Tsao, , Margitta Elvers

This study shows platelets worsen AAA by promoting inflammation, ECM degradation, and osteopontin release, with platelet depletion reducing aneurysm growth.

Cardiovascular Research · Nov 17, 2023Peer-reviewedMolecular Biology