Molecular BiologyCardiovascular ResearchPeer-reviewed
Crosstalk of platelets with macrophages and fibroblasts aggravates inflammation, aortic wall stiffening, and osteopontin release in abdominal aortic aneurysm
Markus Udo Wagenhäuser, Joscha U Mulorz, Kim Jürgen Krott…·Margitta Elvers
This study shows platelets worsen AAA by promoting inflammation, ECM degradation, and osteopontin release, with platelet depletion reducing aneurysm growth.