Author

Hwa-Jin Cho

Seoul National University

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Biology Disciplines

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Dong Kyu Chung· 1 shared Hyung Ho LeeiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiochemistry

Dong Kyu Chung

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedOct 25, 2024

Mefloquine-induced conformational shift in Cx36 N-terminal helix leading to channel closure mediated by lipid bilayer

Hwa-Jin Cho, Dong Kyu Chung, Hyung Ho Lee

The paper presents cryo-EM structures of Cx36 gap junction channels bound to inhibitors, showing how these molecules induce conformational changes leading to channel closure.

5 citations

humancryo-EM

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