Chloride binding to prestin does not influence very high-frequency complex nonlinear capacitance (cNLC) in the mouse outer hair cell
J.-P. Bai, C. Zhang, I. Bahader, N. Strenzke, V. Renigunta, D. Oliver, D. S. Navaratnam, O. Beckstein, J. Santos-Sacchi
This study shows chloride binding does not affect very high-frequency nonlinear capacitance in mouse outer hair cells, suggesting mechanical loads, not anion interactions, govern high-frequency prestin function.
bioRxiv · Jan 29, 2024 · PreprintBiophysics