ImmunologybioRxiv
Use of IL-6-elafin genetically modified regulatory macrophages as an immunotherapeutic against acute bacterial infection in the lung
S. Kheir, B. Villeret, I. Garcia-Verdugo, J.-M. Sallenave
This paper demonstrates that genetically modified macrophages expressing IL-6 and Elafin protect mice from Pseudomonas aeruginosa lung infection by inducing a regulatory immune response.
DOI 10.1016/j.rmr.2021.02.031