Author

I. Irnov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Assay:imaging· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:E. coli· 1

Frequent Co-Authors

C. Jacobs-Wagner· 3 shared C. N. Takacs· 2 shared M. Scott· 2 shared P. A. Rosa· 2 shared F. Cornet· 1 shared G. S. Dobihal· 1 shared J. Liu· 1 shared J. Wachter· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

C. Jacobs-Wagner

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Polyploidy, regular patterning of genome copies, and unusual control of DNA partitioning in the Lyme disease spirochete

C. N. Takacs, J. Wachter, Y. Xiang, X. Karaboja, R. Zhongqing, M. Scott, M. R. Stoner, I. Irnov, N. Jannetty, P. A. Rosa, X. Wang, C. Jacobs-Wagner

This study shows that Borrelia burgdorferi is polyploid in culture and ticks, with regular genome copy spacing controlled by ParA/ParZ and ParB/SMC systems.

bioRxiv · Jul 5, 2022Microbiology

A CRISPR interference platform for selective downregulation of gene expression in Borrelia burgdorferi

C. N. Takacs, M. Scott, Y. Chang, Z. A. Kloos, I. Irnov, P. A. Rosa, J. Liu, C. Jacobs-Wagner

This paper develops a CRISPR interference platform for efficient gene downregulation in Borrelia burgdorferi, demonstrating >95% repression efficiency for multiple genes and revealing roles in motility and cell division.

bioRxiv · Oct 12, 2020Microbiology

Genome-wide phenotypic analysis of growth, cell morphogenesis and cell cycle events in Escherichia coli.

M. Campos, S. K. Govers, I. Irnov, G. S. Dobihal, F. Cornet, C. Jacobs-Wagner

The paper performs a genome-wide screen of Escherichia coli single-gene knockouts to uncover genes involved in cell morphogenesis, growth, and cell cycle, revealing scaling relationships between nucleoid size and cell cycle events.

bioRxiv · Apr 9, 2018Microbiology