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I. J. Kimsey

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:whole-genome sequencing· 1

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A. Rangadurai· 1 shared B. Liu· 1 shared H. Abou Assi· 1 shared H. M. Al-Hashimi· 1 shared H. Shi· 1 shared H. Zhou· 1 shared J. D. Boom· 1 shared Y. Xu· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperBiophysics

A. Rangadurai

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BiophysicsbioRxivPreprintDec 26, 2020

Measuring thermodynamic preferences to form non-native conformations in nucleic acids using melting experiments reveals a rich sequence-specific DNA conformational landscape

A. Rangadurai, H. Shi, Y. Xu…·H. M. Al-Hashimi

This paper introduces delta-melt, a method using chemical modifications and melting experiments to measure thermodynamic preferences for non-native DNA conformations, revealing sequence-specific variations in conformational stability.

DOI 10.1101/2020.12.26.424438

DNA methylationwhole-genome sequencing

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