BiochemistrybioRxiv
Mechanism Underlying Anti-Markovnikov Addition in the Reaction of Pentalenene Synthase
J. O. Matos, R. P. Kumar, A. C. Ma…·D. D. Oprian
The paper elucidates the mechanism of anti-Markovnikov addition in pentalenene synthase by solving crystal structures and showing how residue F76 stabilizes the carbocation through cation-π interactions.
DOI 10.1021/acs.biochem.0c00518