Cancer BiologybioRxiv
The PNUTS-PAD domain recruits MYC to the PNUTS:PP1 phosphatase complex via the oncogenic MYC-MB0 region
Y. Wei, A. Ahlner, C. Redel…·L. Z. Penn
This paper identifies the MB0 region of MYC as a direct binder to the PNUTS amino-terminal domain (PAD), revealing a molecular mechanism for MYC regulation by the PNUTS:PP1 phosphatase complex.
DOI 10.1093/nar/gkac138