L. Z. Penn

This study investigates how N-glycosylation sites on SLC3A2 evolve and regulate amino acid transport and redox balance, revealing their role in cellular trafficking and bird evolution.

This paper identifies the MB0 region of MYC as a direct binder to the PNUTS amino-terminal domain (PAD), revealing a molecular mechanism for MYC regulation by the PNUTS:PP1 phosphatase complex.

This study creates an in vivo model of MYC-driven breast cancer by combining PIK3CAH1047R mutation with deregulated MYC, showing a normal-to-tumour switch and dependence on MYC for tumor growth.