BioengineeringbioRxiv
Epithelial-stromal cell interactions and ECM mechanics drive the formation of airway-mimetic tubular morphology in lung organoids
T. G. Guney, A. Muinelo Herranz, S. Mumby…·I. M. Adcock
This study shows that epithelial-stromal interactions and ECM mechanics guide the formation of airway-like tubules in lung organoids, enabling long-term structure and contractile function.
DOI 10.1016/j.isci.2021.103061