Author

I. R. Short

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

L. Pellegrini· 1 shared M. Jenkyn-Bedford· 1 shared M. L. Kilkenny· 1 shared N. J. Rzechorzek· 1 shared S. Holzer· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

L. Pellegrini

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1 paper

Recent·Most cited

BiochemistrybioRxivApr 11, 2019

Structural basis for inhibition of human primase by arabinofuranosyl nucleoside analogues Fludarabine and Vidarabine

S. Holzer, N. J. Rzechorzek, I. R. Short…·M. L. Kilkenny

This study provides a structural basis for how Fludarabine and Vidarabine inhibit human primase, suggesting ways to improve their therapeutic efficacy and reduce toxicity.

DOI 10.1021/acschembio.9b00367

humanstructural biology

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