MicrobiologybioRxiv
The PqsE active site as a target for small molecule antimicrobial agents against Pseudomonas aeruginosa
I. R. Taylor, P. D. Jeffrey, D. A. Moustafa…·B. L. Bassler
This paper shows that disrupting the PqsE-RhlR interaction reduces P. aeruginosa infection in mice and presents new molecules targeting the PqsE active site.
DOI 10.1021/acs.biochem.2c00334