Author

I. Roditi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Naguleswaran· 2 shared M. Benninger· 2 shared A. Jenni· 1 shared A. K. Menon· 1 shared B. Nickel· 1 shared D. Abbuehl· 1 shared L. Jenni· 1 shared M. A. J. Ferguson· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

A. Naguleswaran

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Trypanosoma brucei: A novel system for metacyclogenesis and complete cyclical development in vitro

B. Nickel, M. Fasler, R. Brun, R. Kaminsky, I. Roditi, L. Jenni

This paper describes an in vitro system for metacyclogenesis of Trypanosoma brucei ssp. that allows complete cyclical development and transformation to infective forms.

bioRxiv · Jan 18, 2022 · PreprintMicrobiology

Developmental changes and metabolic reprogramming during establishment of infection and progression of Trypanosoma brucei brucei through its insect host

A. Naguleswaran, P. Fernandes, S. Bevkal, R. Rehmann, P. Nicholson, I. Roditi

This paper presents a genome assembly and transcriptome analysis of T. brucei brucei EATRO1125, revealing developmental changes and metabolic reprogramming during its life cycle in the tsetse fly.

bioRxiv · May 26, 2021Microbiology

Elimination of GPI2 suppresses glycosylphosphatidylinositol GlcNAc transferase activity and alters GPI glycan modification in Trypanosoma brucei

A. Jenni, S. Knüsel, R. Nagar, M. Benninger, R. Häner, M. A. J. Ferguson, I. Roditi, A. K. Menon, P. Bütikofer

This study shows that eliminating GPI2 in Trypanosoma brucei reduces GPI GlcNAc transferase activity, alters GPI glycan modification, and affects social motility.

bioRxiv · Mar 18, 2021Biochemistry

Cyclic AMP signalling and glucose metabolism mediate pH taxis by African trypanosomes

S. Shaw, S. Knuesel, D. Abbuehl, A. Naguleswaran, R. Etzensperger, M. Benninger, I. Roditi

This study shows that African trypanosomes use pH gradients mediated by cyclic AMP signalling and glucose metabolism for taxis, with implications for their infection establishment.

bioRxiv · Jan 1, 2021Microbiology