Author

I. S. Fonseca

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. S. Ribeiro· 1 shared B. Sousa· 1 shared C. Horta· 1 shared G. Marteil· 1 shared J. Paredes· 1 shared M. Bettencourt Dias· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

A. S. Ribeiro

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintDec 16, 2022

Polo-like kinase 4 (Plk4) potentiates anoikis-resistance of p53KO mammary epithelial cells by inducing a hybrid EMT phenotype

I. S. Fonseca, C. Horta, A. S. Ribeiro…·J. Paredes

This study shows Plk4 promotes anoikis resistance in p53KO mammary epithelial cells through a hybrid EMT phenotype and P-cadherin upregulation, acting as an oncogene independent of centrosome biogenesis.

DOI 10.1101/2022.12.16.520613

mouseexperimental assay

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