BiochemistrybioRxiv
Colloidal aggregation confounds cell-based Covid-19 antiviral screens
I. S. Glenn, L. N. Hall, M. M. Khalid…·B. K. Shoichet
The paper investigates how colloidal aggregation affects cell-based antiviral screens for Covid-19 drugs, finding that aggregation reduces antiviral potency and suggests a non-specific mechanism.
DOI 10.1021/acs.jmedchem.4c00597