Polymer Model Unveils Quantitative Association of Chromatin Conformation and Gene Regulation
S. Senapati, I. Shah, A. K. Sharma, H. Kumar
The paper introduces a computational framework linking chromatin structure to gene regulation using polymer models and Hi-C data, showing how CTCF deletion affects gene expression in limb development.
bioRxiv · Dec 4, 2023 · PreprintBiophysics