Cell BiologybioRxivPreprint
Systemic Lupus Erythematosus Serum Stimulation of Human Intestinal Organoids Induces Changes in Goblet Cell Differentiation and Mitochondrial Fitness
I. V. Hensel, S. Elias, M. Steinhauer…·M. Resnik-Docampo
This study shows that SLE serum affects intestinal organoids by altering mucus, mitochondrial fitness, and gene expression, linking gut barrier dysfunction to autoimmune disease.
DOI 10.1101/2023.07.04.547690