Irene E. Whitney

This study uses scRNA-seq to analyze molecular maturation of mouse retinal ganglion cells, showing visual activity is not required for type identity but is needed for full maturation.

This study uses single-cell RNA-seq to show that mouse retinal ganglion cell precursors diversify into discrete types through gradual fate restriction after mitosis.

This paper identifies 63 amacrine cell types in the mouse retina using scRNA-seq and provides molecular markers, neurotransmitter profiles, and transcription factors for each type.

The paper identifies neuroprotective genes in retinal ganglion cells by analyzing their resilience to injury using single-cell RNA-seq and functional assays.

The paper maps transgene insertion sites in mice and shows that transgene integration affects neighboring endogenous gene expression.