Author

J. A. Gallaher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

A. R. A. Anderson· 2 shared A. C. Hawkins-Daarud· 1 shared C. J. Whelan· 1 shared J. Juliano· 1 shared J. S. Brown· 1 shared K. A. Luddy· 1 shared K. R. Swanson· 1 shared L. Gonzalez-Cuyar· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. R. A. Anderson

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3 papers

Recent·Most cited

Cancer BiologybioRxivOct 28, 2020

Cycling hypoxia selects for constitutive HIF stabilization

M. Pressley, J. A. Gallaher, J. S. Brown…·C. J. Whelan

The paper develops a mathematical model showing that rapid oxygen fluctuations favor pseudohypoxia by selecting for constitutive HIF stabilization despite reduced cell fitness.

DOI 10.1038/s41598-021-85184-8

statistical model

𝕏 PostBluesky

Cancer BiologybioRxivMay 26, 2019

From cells to tissue: How cell scale heterogeneity impacts glioblastoma growth and treatment response

J. A. Gallaher, S. C. Massey, A. C. Hawkins-Daarud…·A. R. A. Anderson

This paper develops a hybrid agent-based model to study how intratumor heterogeneity affects glioblastoma growth and treatment response using multiscale data and mathematical frameworks.

DOI 10.1371/journal.pcbi.1007672

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivSep 8, 2017

Spatial heterogeneity and evolutionary dynamics modulate time to recurrence in continuous and adaptive cancer therapies

J. A. Gallaher, P. M. Enriquez-Navas, K. A. Luddy…·A. R. A. Anderson

This study models how spatial heterogeneity and evolutionary dynamics affect cancer recurrence under different treatment schedules.

DOI 10.1158/0008-5472.can-17-2649

experimental assaycancer & tumor microenvironment

𝕏 PostBluesky