MicrobiologybioRxiv
HIV-1 Vpu restricts Fc-mediated effector functions in vivo
J. Prevost, S. P. Anand, J. K. Rajashekar…·A. Finzi
This study shows that HIV-1 Vpu reduces nnAb recognition and ADCC resistance, with nnAb Fc-effector functions dependent on Env's open conformation.
DOI 10.1016/j.celrep.2022.111624