Author

J. A. Hoxie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:non-human primate· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:variant calling· 1

Frequent Co-Authors

D. Szeltner· 2 shared F. Schiro· 2 shared L. A. Doyle-Meyers· 2 shared N. J. Maness· 2 shared P. P. Aye· 2 shared R. V. Blair· 2 shared A. A. Lackner· 1 shared A. Melton· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

D. Szeltner

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2 papers

Recent·Most cited

ImmunologybioRxivAug 28, 2021

The pigtail macaque (Macaca nemestrina) model of COVID-19 reproduces diverse clinical outcomes and reveals new and complex signatures of disease

A. Melton, L. A. Doyle-Meyers, R. V. Blair…·N. J. Maness

This study shows that pigtail macaques infected with SARS-CoV-2 exhibit mild-to-moderate disease with specific immune and viral dynamics, making them a potential model for studying COVID-19.

DOI 10.1371/journal.ppat.1010162

non-human primateexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintMar 31, 2021

A tyrosine-based trafficking signal in the simian immunodeficiency virus envelope cytoplasmic domain is strongly selected for in pathogenic SIV infection

S. Lawrence, S. E. Elser, W. Torben…·J. A. Hoxie

This study shows that a tyrosine-based trafficking signal in SIV Env is strongly selected for during pathogenic infection, as mutations reconstitute endocytosis and polarized sorting signals.

DOI 10.1101/2021.03.31.437834

non-human primateexperimental assay

𝕏 PostBluesky