Differential cross-reactivity to the influenza B virus haemagglutinin underpins lineage-specific susceptibility between birth cohorts
P. Edler, L. S. U. Schwab, M. Aban, M. Wille, N. Spirason, Y.-M. Deng, M. A. Carlock, T. Ross, J. A. Juno, S. Rockman, A. K. Wheatley, S. J. Kent, I. Barr, D. J. Price, M. Koutsakos
The paper shows that early life exposure to influenza B virus influences cross-reactivity and susceptibility to future isolates, explaining lineage-specific infection patterns across birth cohorts.
bioRxiv · Aug 25, 2023 · PreprintImmunology