Author

C. Ameel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Organism:non-human primate· 5 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Assay:flow cytometry· 1

Frequent Co-Authors

P. Maiello· 5 shared A. J. Balgeman· 3 shared C. Scanga· 3 shared M. Rodgers· 3 shared A. G. White· 2 shared A. L. Ellis· 2 shared C. A. Scanga· 2 shared E. C. Larson· 2 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersImmunology

P. Maiello

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Author profile →

5 papers

Recent·Most cited

Host Immunity to Mycobacterium tuberculosis Infection is Similar in Simian Immunodeficiency Virus (SIV)-infected, Antiretroviral Therapy-treated and SIV-naïve Juvenile Macaques

E. C. Larson, A. L. Ellis-Connell, M. Rodgers, A. K. Gubernat, J. L. Gleim, R. V. Moriarty, A. J. Balgeman, Y. K. Menezes, C. Ameel, D. J. Filmore, S. M. Pergalske, J. A. Juno, P. Maiello, A. G. White, H. J. Borish, , C. A. Scanga

This study compares host immunity to Mycobacterium tuberculosis in SIV-infected, ART-treated and SIV-naïve juvenile macaques, finding similar TB progression and T cell responses.

bioRxiv · Dec 14, 2022 · PreprintImmunology

Pre-existing SIV infection increases expression of T cell markers associated with activation during early Mycobacterium tuberculosis co-infection and impairs TNF responses in granulomas

E. Larson, A. L. Ellis, M. A. Rodgers, A. J. Balgeman, R. V. Moriarty, C. Ameel, T. Baranowski, J. Tomko, C. Causgrove, P. Maiello, S. L. OConnor, C. A. Scanga

This study shows that pre-existing SIV infection alters T cell phenotypes and reduces TNF responses during early Mtb co-infection, impairing immune control.

bioRxiv · Dec 14, 2020Immunology

Multimodal profiling of lung granulomas reveals cellular correlates of tuberculosis control

H. P. Gideon, T. K. Hughes, C. N. Tzouanas, M. H. Wadsworth, A. A. Tu, T. M. Gierahn, J. M. Peters, F. H. Hopkins, J.-R. Wei, C. Kummerlowe, N. L. Grant, K. Nargan, J. Phuah, H. J. Borish, P. Maiello, , A. K. Shalek

The paper identifies cellular and temporal factors associated with bacterial control in tuberculosis granulomas using multimodal data.

bioRxiv · Oct 24, 2020 · PreprintImmunology

MAIT cells are minimally responsive to Mycobacterium tuberculosis within granulomas, but are functionally impaired by SIV in a macaque model of SIV and Mtb co-infection

A. L. Ellis, A. J. Balgeman, E. C. Larson, M. Rodgers, C. Ameel, T. Baranowski, P. Maiello, J. Juno, C. Scanga, S. L. O'Connor

This study examines MAIT cell function in a macaque model of SIV and Mtb co-infection, finding minimal Mtb responsiveness within granulomas and impaired TNF secretion during co-infection.

bioRxiv · Jan 7, 2020 · PreprintImmunology

Pre-existing SIV Infection Increases Susceptibility to Tuberculosis in Mauritian Cynomolgus Macaques

M. Rodgers, C. Ameel, A. Ellis-Connell, A. Balgeman, P. Maiello, G. Barry, T. Friedrich, E. Klein, S. O'Connor, C. Scanga

This study shows that pre-existing SIV infection in macaques increases susceptibility to tuberculosis by impairing immune control of M.tb.

bioRxiv · Jul 3, 2018Immunology