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J. A. Owen

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Biophysics· 1

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Approach:biophysical modeling· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

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D. Osmanovic· 1 shared L. A. Mirny· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperBiophysics

D. Osmanovic

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1 paper

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BiophysicsbioRxivSep 24, 2022

Design principles of 3D epigenetic memory systems

J. A. Owen, D. Osmanovic, L. A. Mirny

This study shows how 3D genome compartmentalization and enzyme limitation stabilize epigenetic memory through a biophysical model of histone mark spreading.

DOI 10.1126/science.adg3053

ChIP-seqbiophysical modeling

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