MicrobiologybioRxivPreprint
Bioactive Natural Product Discovery via Deuterium Adduct Bioactivity Screening
N. A. Zill, Y. Du, S. Marinkovich…·W. Zhang
This paper introduces DABS, a new workflow for natural product discovery that combines isotope labeling with whole cell binding assays, leading to the identification of zillamycin with anti-cancer and anti-microbial activities.
DOI 10.1101/2023.03.16.532988