D. Gu

Jianpi Jiedu Recipe inhibits proliferation through reactive oxygen species-induced incomplete autophagy and reduces PD-L1 expression in colon cancer

Dispersal and evolution of the invasive snail Pomacea canaliculata, an intermediate host of Angiostrongylus cantonensis: A field study around its initial introduction site in China

This study investigates the spatial distribution, phenotypic variation, and dispersal patterns of the invasive snail Pomacea canaliculata in China, revealing human-mediated evolution and potential complexities in parasite transmission.

Mutation divergence over space in tumour expansion

This study quantifies how mutation divergence varies with sampling distance and tumour expansion modes using simulations, showing that mutation rate inference is less accurate with smaller sampling sizes and slower expansion.

Bioactive Natural Product Discovery via Deuterium Adduct Bioactivity Screening

This paper introduces DABS, a new workflow for natural product discovery that combines isotope labeling with whole cell binding assays, leading to the identification of zillamycin with anti-cancer and anti-microbial activities.

Previously unrecognized non-reproducible antibody-antigen interactions and their implications for diagnosis of viral infections including COVID-19

The paper identifies non-reproducible antibody-antigen interactions in clinical sera and develops a model to explain them, improving serological testing for viral infections like COVID-19.

Profiles of Expression pattern and tissue distribution of host defense peptides genes in different chicken (Gallus gallus) breeds related to body weight

The paper examines HDP gene expression and tissue distribution in different chicken breeds, finding correlations between body weight, age, and HDP expression in immune organs and intestine.

Discovery and biosynthesis of clostyrylpyrones from the obligate anaerobe Clostridium roseum

The paper discovers a new family of natural products, clostyrylpyrones, from Clostridium roseum and proposes their polyketide synthase-based biosynthesis mechanism.

IDENTIFICATION AND CHARACTERIZATION OF A LARGE SOURCE OF PRIMARY MESENCHYMAL STEM CELLS TIGHTLY ADHERED TO BONE SURFACES OF HUMAN VERTEBRAL BODY MARROW CAVITIES

The paper identifies and characterizes a large source of primary mesenchymal stem cells (MSC) tightly adhered to bone surfaces in human vertebral body marrow cavities, demonstrating their potential to reduce manufacturing costs and variability in MSC therapy.