Author

J. Aspden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Whitehouse· 2 shared T. J. Mottram· 2 shared A. Macdonald· 1 shared A. R. Leach· 1 shared B. Baquero-Perez· 1 shared C. J. Trevelyan· 1 shared E. Harrington· 1 shared E. Vasconcelos· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. Whitehouse

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

m6A regulates the stability of cellular transcripts required for efficient KSHV lytic replication

O. Manners, B. Baquero-Perez, T. J. Mottram, I. D. Yonchev, C. J. Trevelyan, M. R. Patterson, A. Macdonald, S. A. Wilson, J. Aspden, A. Whitehouse

This study shows m6A modification stabilizes GPRC5A mRNA, which promotes KSHV lytic replication by enhancing NF-κB signaling.

bioRxiv · Feb 9, 2023 · PreprintMicrobiology

Kaposi's sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs

J. C. Murphy, S. Schumann, E. Harrington, E. Vasconcelos, T. J. Mottram, J. Aspden, A. Whitehouse

This study shows Kaposi's sarcoma-associated herpesvirus manipulates host ribosome composition to create specialised ribosomes that enhance translation of viral lytic mRNAs.

bioRxiv · Mar 11, 2022Microbiology

Ribosome fingerprinting with a solid-state nanopore

M. Raveendran, A. R. Leach, T. S. Hopes, J. Aspden, P. Actis

This study uses solid-state nanopores to distinguish 80S ribosomes from polysomes in human and Drosophila cells based on peak amplitude and dwell time.

bioRxiv · Aug 7, 2020Biophysics