A. Whitehouse

HOP/STIP1 is required for KSHV lytic replication.

This study shows HOP/STIP1 is essential for KSHV lytic replication in primary effusion cell lines.

m6A regulates the stability of cellular transcripts required for efficient KSHV lytic replication

This study shows m6A modification stabilizes GPRC5A mRNA, which promotes KSHV lytic replication by enhancing NF-κB signaling.

Pseudouridine prevalence in Kaposi's sarcoma associated herpesvirus transcriptome reveals an essential mechanism for viral replication

This study identifies pseudouridylation as essential for Kaposi's sarcoma-associated herpesvirus replication by analyzing its role in viral RNA stability and protein interactions.

Exploitation of ATP-sensitive potassium ion (KATP) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling

This study shows that HPV exploits KATP channels to promote cervical cancer cell proliferation through MAPK/AP-1 signaling.

Epistatic Modifiers Influence the Expression of Continual Flowering in Strawberry

This study identifies epistatic modifiers that influence the expression of continual flowering in strawberries, improving segregation ratio predictions beyond a single allele model.

Kaposi's sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs

This study shows Kaposi's sarcoma-associated herpesvirus manipulates host ribosome composition to create specialised ribosomes that enhance translation of viral lytic mRNAs.

Investigating the structural changes due to adenosine methylation of the Kaposi's sarcoma-associated herpes virus ORF50 transcript

The paper examines how adenosine methylation affects the structural stability of the KSHV ORF50 RNA stem loop by comparing energy landscapes of methylated and unmethylated forms.

CircHIPK3 dysregulation of the miR-30c/DLL4 axis is essential for KSHV lytic replication

The paper identifies a host ncRNA regulatory network involving circHIPK3 and miR-30c/DLL4 that is essential for KSHV lytic replication in B cells.

Kv1.3 induced hyperpolarisation and Cav3.2-mediated calcium entry are required for efficientKaposi's sarcoma-associated herpesvirus lytic replication

The paper identifies Kv1.3 and Cav3.2 ion channels as essential for KSHV lytic replication by promoting Ca2+ influx and NFAT activation.

The Genetic Architecture of Strawberry Yield and Fruit Quality Traits

This study identifies genetic factors influencing strawberry yield and quality traits, finding a trade-off between sugar content and yield and recommending trait selection strategies for breeding.

Merkel Cell Polyomavirus Small Tumor Antigen Activates Matrix Metallopeptidase-9 Gene Expression for Cell Migration and Invasion

This study shows MCV sT activates MMP-9 expression via the LSD domain, promoting cell migration and invasion in MCC, suggesting MMP-9 as a therapeutic target.

A requirement for Potassium and Calcium Channels during the Endosomal Trafficking of Polyomavirus Virions

This study identifies the role of K+ and Ca2+ channels in polyomavirus infection, showing that Ca2+ channels are essential for both SV40 and MCPyV, while MCPyV is also sensitive to K+ channel blockage.