Author

E. Harrington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Microbiology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:development & morphogenesis· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:ecology & biodiversity· 2 Organism:human· 2 Organism:plant (other)· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

S. Juul· 4 shared X. Dai· 4 shared J. Beaulaurier· 2 shared J. Y. Choi· 2 shared M. Purugganan· 2 shared P. Rughani· 2 shared S. Hickey· 2 shared A. Corno· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersEvolutionary Biology

S. Juul

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Single-cell multi-omics defines the cell-type specific impact of splicing aberrations in human hematopoietic clonal outgrowths

F. Gaiti, P. Chamely, A. G. Hawkins, M. Cortes-Lopez, A. D. Swett, S. Ganesan, T. H. Mouhieddine, X. Dai, L. Kluegel, C. Chen, K. Batta, J. Beaulaurier, A. W. Drong, S. Hickey, N. Dusaj, , D. A. Landau

This study introduces GoT-Splice, a multi-omics method to analyze splicing aberrations in human hematopoietic cells, revealing cell-type specific effects of SF3B1 mutations in clonal outgrowths.

bioRxiv · Jun 8, 2022 · PreprintCancer Biology

A bifunctional kinase-phosphatase module integrates mitotic checkpoint and error-correction signalling to ensure mitotic fidelity

A. Corno, M. H. Cordeiro, L. A. Allan, Q. W. Lim, E. Harrington, R. J. Smith, A. T. Saurin

This study shows that the PLK1-PP2A kinase-phosphatase pair regulates mitotic checkpoint and error-correction signaling through feedback on the BUB complex, ensuring proper chromosome segregation.

bioRxiv · May 22, 2022Cell Biology

Kaposi's sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs

J. C. Murphy, S. Schumann, E. Harrington, E. Vasconcelos, T. J. Mottram, J. Aspden, A. Whitehouse

This study shows Kaposi's sarcoma-associated herpesvirus manipulates host ribosome composition to create specialised ribosomes that enhance translation of viral lytic mRNAs.

bioRxiv · Mar 11, 2022Microbiology

Selection on ancient variations drives the adaptive radiation of Metrosideros across the Hawaiian archipelago

J. Y. Choi, X. Dai, J. Z. Peng, P. Rughani, S. Hickey, E. Harrington, S. Juul, J. Ayroles, M. Purugganan, E. Stacy

This study investigates how ancient genetic variations drive adaptive radiation in Hawaiian Metrosideros, showing balancing selection on pre-existing haplotypes facilitates diversification despite limited genetic diversity.

bioRxiv · Nov 3, 2020 · PreprintEvolutionary Biology

Nanopore-based genome assembly and the evolutionary genomics of basmati rice

J. Y. Choi, Z. Lye, S. Groen, X. Dai, P. Rughani, S. Zaaijer, E. Harrington, S. Juul, M. Purugganan

The paper assembles high-quality genomes of two basmati rice varieties using nanopore sequencing and identifies structural variations, gene flow, and genetic groupings in circum-basmati rice.

bioRxiv · Aug 13, 2019 · PreprintEvolutionary Biology

Assembly-free single-molecule nanopore sequencing recovers complete virus genomes from natural microbial communities

J. Beaulaurier, E. Luo, J. Eppley, P. Den Uyl, X. Dai, D. J. Turner, M. Pendleton, S. Juul, E. Harrington, E. F. DeLong

This study develops an assembly-free nanopore sequencing method to recover complete virus genomes from environmental samples, revealing new viral structures and genomic features.

bioRxiv · Apr 26, 2019Microbiology