Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
C. Chau, C. Maffeo, A. Aksimentiev, S. Radford, E. Hewitt, P. Actis
This paper introduces a nanoinjection platform using nanopipettes to deliver macromolecules into cells with single molecule resolution, showing phenotypic changes and enhanced detection through macromolecular crowding.
bioRxiv · Jan 9, 2024Biophysics
C. Chau, G. Mohanan, I. C. Macaulay, P. Actis, C. Walti
This paper introduces SPRI beads as an automated, scalable method for purifying DNA origami, achieving comparable yield and structural integrity while enabling high-throughput processing.
bioRxiv · Jul 5, 2023Biophysics
S. Confederat, S. Lee, D. Vang, D. Soulias, F. Marcuccio, T. I. Peace, M. A. Edwards, P. Strobbia, D. Samanta, C. Walti, P. Actis
This paper develops enhanced nanopore sensors with a polymer electrolyte system to analyze heterogeneous nanoparticle mixtures at low ionic strength, demonstrating their applicability to various nanoparticle types.
bioRxiv · Mar 31, 2023 · PreprintBiophysics
F. Marcuccio, D. Soulias, C. C. Chau, S. Radford, E. Hewitt, P. Actis, M. Edwards
This study investigates how adding PEG to the external solution enhances nanopore signal detection by altering ion transport and interface displacement.
bioRxiv · Aug 17, 2022 · PreprintBiophysics
S. Confederat, I. Sandei, G. Mohanan, C. Walti, P. Actis
This paper demonstrates nanopore-based fingerprinting of DNA origami nanostructures to quantify assembly yields with single-molecule resolution, showing improved performance over agarose gel electrophoresis and AFM.
bioRxiv · Jun 23, 2022Biophysics
C. C. Chau, F. Marcuccio, D. Soulias, M. A. Edwards, S. E. Radford, E. W. Hewitt, P. Actis
This paper enhances nanopore signal-to-noise ratio by modifying the solution with PEG and optimizing the supporting electrolyte, enabling detection of short dsDNA.
bioRxiv · Nov 1, 2021Biophysics