BiochemistrybioRxiv
A binary arginine methylation switch on histone H3 Arginine 2 regulates its interaction with WDR5
B. M. Lorton, R. K. Harijan, E. S. Burgos…·D. Shechter
The paper investigates how arginine methylation states of H3R2 regulate its interaction with WDR5, revealing a binary switch mechanism where me2a blocks binding while me0/me1/me2s allow it.
DOI 10.1021/acs.biochem.0c00035