Author

J. B. Chaires

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:mechanistic / dynamical model· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

J. O. Trent· 2 shared W. L. Dean· 2 shared L. W. DeLeeuw· 1 shared R. C. Monsen· 1 shared R. D. Gray· 1 shared R. Monson· 1 shared S. Chakravarthy· 1 shared V. Stribinskis· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

J. O. Trent

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2 papers

Recent·Most cited

BiophysicsbioRxivNov 13, 2020

The solution structures of higher-order human telomere G-quadruplex multimers

R. C. Monsen, S. Chakravarthy, W. L. Dean…·J. O. Trent

The paper determines the solution structures of higher-order human telomere G-quadruplex multimers using structural biology methods and finds they are semi-flexible with mixed G4 conformers and potential drug targeting sites.

DOI 10.1093/nar/gkaa1285

humanstructural biology

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BiophysicsbioRxivJul 2, 2019

Human POT1 Unfolds G-Quadruplexes by Conformational Selection

J. B. Chaires, R. D. Gray, W. L. Dean…·J. O. Trent

This paper investigates how POT1 unfolds human telomeric G-quadruplexes through a conformational selection mechanism, supported by kinetic, thermodynamic, and computational data.

DOI 10.1093/nar/gkaa202

humanexperimental assay

𝕏 PostBluesky