Role of HNF4alpha-cMyc Interaction in CDE-diet Induced Liver Injury and Regeneration
M. Kotulkar, J. Barbee, D. Robarts, D. Paine-Cabrera, U. Apte
This study examines the role of HNF4-cMyc interaction in liver injury and regeneration using a CDE diet model, finding that HNF4 deletion increases injury while cMyc deletion decreases it, with combined deletion leading to a unique HPC activation phenotype.
bioRxiv · Nov 27, 2023Pathology