J. Borrego-Pinto

This study maps spatiotemporal changes in cellular tensions during early C. elegans embryo development using a hybrid inference pipeline validated with AFM and live microscopy.

The paper shows that PAR protein segregation by cortical flows depends on membrane association stability rather than oligomer size, and demonstrates this through experiments and theory.

SAIBR corrects autofluorescence in imaging data using a simple, platform-independent method, enabling accurate quantification of weakly expressed proteins across diverse systems.