Author

J. Breuning

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. B. Parekh· 1 shared A. G. Grieve· 1 shared K. Strisovsky· 1 shared L. Zarcone· 1 shared M. Freeman· 1 shared M. H. Brown· 1 shared N. Johnson· 1 shared Y.-C. Yeh· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

A. B. Parekh

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1 paper

Recent·Most cited

Conformational surveillance of Orai1 by a rhomboid intramembrane protease prevents inappropriate CRAC channel activation

A. G. Grieve, Y.-C. Yeh, L. Zarcone, J. Breuning, N. Johnson, K. Strisovsky, M. H. Brown, A. B. Parekh, M. Freeman

The paper identifies RHBDL2 as a rhomboid protease that surveils and cleaves active Orai1 to prevent inappropriate CRAC channel activation, maintaining proper T cell signaling.

bioRxiv · Apr 4, 2020Biochemistry