Author

J. C. Eickhoff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Animal Behavior & Cognition· 1 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 5 Organism:rat· 5 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:imaging· 2 Organism:non-human primate· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

E. L. Mohr· 6 shared A. Mejia· 5 shared D. H. O'Connor· 5 shared H. A. Simmons· 5 shared A. M. Mitzey· 4 shared A. M. Weiler· 4 shared C. M. Newman· 4 shared E. Razo· 4 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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6 shared papersMicrobiology

E. L. Mohr

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Frequent first-trimester pregnancy loss in rhesus macaques infected with African-lineage Zika virus

J. R. Rosinski, L. E. Raasch, P. Barros Tiburcio, M. E. Breitbach, P. M. Shepherd, K. Yamamoto, E. Razo, N. P. Krabbe, M. I. Bliss, A. D. Richardson, M. A. Einwalter, A. M. Weiler, E. L. Sneed, K. B. Fuchs, X. Zeng, , N

This study shows that African-lineage ZIKV infection in early first trimester causes high pregnancy loss in rhesus macaques, regardless of SIV status.

bioRxiv · Dec 9, 2022Microbiology

Quantification of Early Gait Development: Expanding the Application of Catwalk Technology to an Infant Rhesus Macaque Model

S. A. Kabakov, E. Crary, V. Menna, E. R. Razo, J. C. Eickhoff, N. R. Dulaney, J. R. Drew, K. Bach, A. M. Poole, M. Stumpf, A. M. Mitzey, K. B. Malicki, M. L. Schotzko, K. A. Pickett, N. J. Schultz-Darken, , K. K. Ausderau

This paper assesses gait development in infant rhesus macaques using the Noldus Catwalk system, finding that diagonal walking patterns emerge early and gait parameters show limited change over the first month.

bioRxiv · Nov 14, 2022Animal Behavior & Cognition

Fetal loss in pregnant rhesus macaques infected with high-dose African-lineage Zika virus

L. Raasch, K. Yamamoto, C. M. Newman, J. R. Rosinski, P. M. Shepherd, E. Razo, C. M. Crooks, M. I. Bliss, M. E. Breitbach, E. L. Sneed, A. M. Weiler, X. Zeng, K. K. Noguchi, T. K. Morgan, N. A. Fuhler, , D. M. Dudley

This study shows that high-dose African-lineage Zika virus infection in late first trimester pregnant rhesus macaques causes frequent fetal loss.

bioRxiv · Mar 21, 2022Pathology

Integrating Subclonal Response Heterogeneity to Define Cancer Organoid Therapeutic Sensitivity

J. D. Kratz, S. Rehman, K. A. Johnson, A. A. Gillette, A. Sunil, P. F. Favreau, C. A. Pasch, D. Miller, L. C. Zarling, A. H. Yeung, L. Clipson, S. J. Anderson, A. K. DeZeeuw, C. M. Sprackling, K. K. Lemmon, , D. A. Deming

The paper evaluates individual patient-derived cancer organoids using optical metabolic imaging to predict therapeutic response and identify subclonal populations and resistance mechanisms.

bioRxiv · Oct 15, 2021 · PreprintCancer Biology

Prior dengue immunity enhances Zika virus infection of the maternal-fetal interface in rhesus macaques

C. M. Crooks, A. M. Weiler, S. L. Rybarczyk, M. I. Bliss, A. S. Jaeger, M. E. Murphy, H. A. Simmons, A. Mejia, M. K. Fritsch, J. M. Hayes, J. C. Eickhoff, A. M. Mitzey, E. Razo, K. M. Braun, E. A. Brown, , M. T. Aliota

This study shows that prior dengue virus immunity enhances Zika virus infection at the maternal-fetal interface in rhesus macaques but does not affect plasma replication or fetal outcomes.

bioRxiv · Jan 25, 2021 · PreprintMicrobiology

African-lineage Zika virus replication dynamics and maternal-fetal interface infection in pregnant rhesus macaques

C. M. Crooks, A. M. Weiler, S. L. Rybarczyk, M. I. Bliss, A. S. Jaeger, M. E. Murphy, H. A. Simmons, A. Mejia, M. K. Fritsch, J. M. Hayes, J. C. Eickhoff, A. M. Mitzey, E. Razo, K. Braun, E. A. Brown, , T. C. Friedrich

This study infects pregnant rhesus macaques with African- and Asian-lineage Zika virus to compare their pathogenesis, finding similar replication kinetics but higher viral burden in maternal-fetal interface tissues with African-lineage isolates.

bioRxiv · Nov 30, 2020Microbiology

Discovery of a novel simian pegivirus in common marmosets (Callithrix jacchus) with lymphocytic enterocolitis

A. S. Heffron, M. Lauck, E. D. Somsen, E. C. Townsend, A. L. Bailey, M. Sosa, J. C. Eickhoff, S. Capuano, C. M. Newman, J. Kuhn, A. Mejia, H. A. Simmons, D. OConnor

The paper discovers a novel simian pegivirus, SOBV, in common marmosets with lymphocytic enterocolitis, finds it prevalent in 34% of healthy marmosets, and notes its presence in clinically-normal marmosets at another center.

Microorganisms · Sep 30, 2020Peer-reviewedMicrobiology

Antibody responses to Zika virus protein in pregnant and non-pregnant macaques

A. S. Heffron, E. L. Mohr, D. Baker, A. K. Haj, C. R. Buechler, A. Bailey, D. Dudley, C. M. Newman, M. S. Mohns, M. Koenig, M. E. Breitbach, M. Rasheed, L. M. Stewart, J. C. Eickhoff, R. S. Pinapati, , D. H. O'Connor

This study profiles anti-ZIKV antibody reactivity in macaques and shows that ZIKV-specific responses can wane over time and may be confused with DENV cross-reactivity.

bioRxiv · Aug 9, 2018Microbiology