A. Bailey

Immunopeptidomics-guided identification of functional neoantigens in non-small cell lung cancer

The paper identifies functional neoantigens in NSCLC patients using immunopeptidomics, achieving an 83% success rate in eliciting immune responses.

Acute, chronic and conditioned effects of intranasal oxytocin in the mu opioid receptor knockout mouse model of autism: social context matters

This study examines the effects of intranasal oxytocin in Oprm1 knockout mice, finding dose- and context-dependent improvements in social behavior and gene expression changes.

Toward Sustainable Biocultural Tourism: An Integrated Spatial Analysis of Cultural and Biodiversity Richness in Colombia

This study maps biocultural tourism potential in Colombia by analyzing spatial correlations between biodiversity and cultural richness, finding that Indigenous reserves and Afro-Colombian territories show high potential.

Identification of neoantigens in esophageal adenocarcinoma

This study identifies neoantigens in esophageal adenocarcinoma, finding one directly presented HLA-I neoantigen and a predicted HLA-II neoantigen with T-cell responses, highlighting challenges in neoantigen detection.

Diet suppresses tumour initiation by maintaining quiescence of mutation-bearing neural stem cells

This study shows that diet can suppress glioblastoma by restoring quiescence in p53-deficient neural stem cells through omega-3 fatty acids.

Isolation of a potently neutralizing and protective human monoclonal antibody targeting yellow fever virus

The paper isolates a human monoclonal antibody that neutralizes yellow fever virus and provides therapeutic protection in animal models.

Immunopeptidomic analysis of influenza A virus infected human tissues identifies internal proteins as a rich source of HLA ligands

A single intranasal or intramuscular immunization with chimpanzee adenovirus vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters.

This study compares intranasal and intramuscular delivery of a chimpanzee adenovirus-vectored SARS-CoV-2 vaccine in hamsters, finding that intranasal immunization provides superior protection against infection and inflammation.

Passage of transmissible cancers in the Tasmanian devil is due to a dominant, shared peptide motif and a limited repertoire of MHC-I allotypes

The paper identifies a shared peptide motif and limited MHC-I diversity in Tasmanian devil transmissible cancers, suggesting a mechanism for immune evasion and vaccine design.

High-density amplicon sequencing identifies community spread and ongoing evolution of SARS-CoV-2 in the Southern United States

This study uses high-density amplicon sequencing to show ongoing SARS-CoV-2 evolution and community spread in a Southern U.S. suburban area, identifying the D614G variant as dominant.

Subclinical infection of macaques and baboons with a baboon simartevirus

This study infects olive baboons and rhesus macaques with SWBV-1, a simartevirus, and finds no disease in either species despite high viral replication and immune responses.

Antibody responses to Zika virus protein in pregnant and non-pregnant macaques

This study profiles anti-ZIKV antibody reactivity in macaques and shows that ZIKV-specific responses can wane over time and may be confused with DENV cross-reactivity.