Author

J. C. Serrano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Barka· 1 shared C. Hajal· 1 shared G. Offeddu· 1 shared J. B. Parker· 1 shared J. Gill· 1 shared J. Shi· 1 shared K. N. Berrios· 1 shared K. S. Gajula· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBiochemistry

A. Barka

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors

K. N. Berrios, A. Barka, J. Gill, J. C. Serrano, P. F. Bailer, J. B. Parker, N. H. Evitt, K. S. Gajula, J. Shi, R. M. Kohli

This study develops hyperactive base editors by exploring Cas9 and AID cooperation, revealing mechanisms that expand mutational diversity and efficiency in base editing.

Nucleic Acids Research · Jan 23, 2024Peer-reviewedBiochemistry

On-chip engineered human lymphatic microvasculature for physio-/pathological transport phenomena studies

J. C. Serrano, M. R. Gillrie, R. Li, S. H. Ishamuddin, R. D. Kamm

This paper develops a microfluidic model of human lymphatic microvasculature to study transport phenomena and immune interactions, showing its utility for disease research and drug screening.

bioRxiv · Mar 6, 2022 · PreprintBioengineering

The effects of luminal and trans-endothelial fluid flows on the extravasation and tissue invasion of tumor cells in a 3D in vitro microvascular platform

C. Hajal, L. Ibrahim, J. C. Serrano, G. Offeddu, R. Kamm

This study examines how different fluid flows affect tumor cell extravasation and invasion in a 3D in vitro model, finding that luminal and trans-endothelial flows enhance these processes.

bioRxiv · Sep 23, 2020Cancer Biology