Author

L. Ibrahim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

C. Hajal· 2 shared G. Offeddu· 2 shared R. Kamm· 2 shared C. Foley· 1 shared C. Li-Ma· 1 shared C. Stanton· 1 shared G. C. Lander· 1 shared J. C. Serrano· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

C. Hajal

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Author profile →

3 papers

Recent·Most cited

Succinylation of a KEAP1 sensor lysine promotes NRF2 activation

L. Ibrahim, C. Stanton, K. Nutsch, T. Nguyen, C. Li-Ma, Y. Ko, G. C. Lander, L. Wiseman, M. J. Bollong

The paper identifies succinylation of KEAP1 lysine 131 as a mechanism to activate NRF2 transcriptional signaling through metabolic regulation.

bioRxiv · May 8, 2023Cell Biology

The effects of luminal and trans-endothelial fluid flows on the extravasation and tissue invasion of tumor cells in a 3D in vitro microvascular platform

C. Hajal, L. Ibrahim, J. C. Serrano, G. Offeddu, R. Kamm

This study examines how different fluid flows affect tumor cell extravasation and invasion in a 3D in vitro model, finding that luminal and trans-endothelial flows enhance these processes.

bioRxiv · Sep 23, 2020Cancer Biology

Glycocalyx-Mediated Vascular Dissemination of Circulating Tumor Cells

G. Offeddu, C. Hajal, C. Foley, Z. Wan, L. Ibrahim, M. Coughlin, R. Kamm

This study shows tumor cells use glycocalyx components to adhere to endothelium and invade stroma, suggesting targeting this pathway could reduce metastasis.

bioRxiv · Apr 28, 2020Cancer Biology